- Pax-2 is required for mesenchyme-to-epithelium conversion during
These inductive interactions between kidney mesenchyme and ureter can be studied in vitro (Grobstein 1953, 1956) and the subsequent changes in particularly with respect to extracellular matrix and epithelium basement membrane components (for review see.
- Angioblast-mesenchyme induction of early kidney development is
In the case of the kidney, interaction of the epithelial ureteric bud with the metanephric mesenchyme, a histologically distinct patch of cells in the urogenital ridge, leads to condensation of the mesenchyme around the branching ureteric bud, and the.
- FGF-7 modulates kidney size
Although the exact number of nephrons that form around each ureteric bud branch is unknown, the extent of ureteric bud growth and branching during development is believed to be proportional to the number of nephrons that eventually form (Saxen, 1987;.
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